More on thiol switches… a novel redox mechanism regulating proteolysis in facultative anaerobes

by Thaís L. S. Araújo*

Protein homeostasis (proteostasis) is fundamental to living organisms and even if we only judge from the number and intricacies of existing mechanisms to deal with this process, one can conclude it is a priority issue for nature [1]. An intriguing problem has been to understand how facultative anaerobic bacteria adapt their proteostatic mechanisms during the transition from anaerobic to aerobic conditions. In a recent article [2,3], it was found that an interesting