Redoxoma Newsletter #3March 2015 Contents Editor's page | by Francisco R. M. LaurindoEditorial Redoxcope | by Alicia KowaltowskiRedox Reactions and the Origin of Life Redoxoma Highlights | by Maria F. ForniMitochondria can dictate your fate, especially if you’re a stem cell Redoxoma Highlights | by Denise de C. FernandesThe hard path towards accurately measuring in vivo enzyme activity: the case of protein disulfide isomerase Redoxoma Highlights | by Fernanda M. da CunhaMitochondria-to-nucleus communication controls mitochondrial activity and stress resistance in yeast Redoxoma Highlights | by Luis. E. S. NettoYes, together we can…. A highly conserved histidine residue in 2-Cys peroxiredoxins acts as a pH sensor for oligomerization Redoxoma Highlights | by Sayuri MiyamotoIs cholesterol bad for mitochondria? Special Highlights | by Carlos FioravantiINTERVIEW Etelvino José Henriques Bechara: On fireflies and mental illnesses The Radical-Free Corner | by Protasio L. da LuzFree radicals: should clinicians pay attention to them? Highlights | by Lia S. NakaoA comprehensive approach to identify redox and non-redox targets of Trx-like proteins Highlights | by Thaís L. S. AraújoMore on thiol switches… a novel redox mechanism regulating proteolysis in facultative anaerobes