The two faces of peroxiredoxins

by Larissa Anastácio da Costa Carvalho

In the antiquity, many cities protected their territories by surrounding fortifications, with giant gates and arches working as unique gateways. The Roman god Janus, known as the protector of entrances or new-beginnings, is represented by a head with two faces in opposite directions. The two faces of Janus symbolize the duality of nature. Well, nature itself is marked by dichotomy. What in nature cannot be good and bad at the same time? That is the origin of the term Janus effect.

A remarkable example of the Janus effect is the mustard gas (1,1-thiobis-2-chloroethane). Used as a chemical weapon during World War I, it causes serious inflammation of the


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Are the antioxidants a good call to prevent cardiovascular disease?

Because free radicals and reactive oxygen species are often not selective and highly reactive, it is reasonable to think that substances that neutralize these molecules, or that counteract free radicals effects, would be beneficial in human health. Interestingly, this is not what the free radical researchers have found so far. The research headed by Professor Francisco Laurindo’s group, at the Instituto do Coração (Incor) Faculdade de Medicina da Universidade de São Paulo (FMUSP), has shown that the use of lipoic acid, a powerful antioxidant and nutritional supplement, increased aorta aneurism


Calls for Applications

Cooperation between Brazilian research foundations and UK Academies stimulates the mobility of young UK scientists to visit research groups in Brazil to short-term (from 7 days to 12 months) and medium to long term (from 6 months to 36 months). For the São Paulo state, it is also offered an opportunity for young investigators from the UK to start a research career in a university or research institution in the State of São Paulo. The required documentation for the proposals must be submitted to FAPESP before October 23, 2015 (<span